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Article

Preparation of biologically active platelet-derived growth factor isoforms AA and AB. Preferential formation of AB heterodimers.

European journal of biochemistry - 12 Jan 1990

Hoppe J, Weich H A, Eichner W, Tatje D

Abstract excerpt

We have expressed the mature platelet-derived growth factor (PDGF) A chain within a fusion protein of the cro repressor and beta-galactosidase in Escherichia coli. Monomeric PDGF-A was excised from this fusion protein by CNBr cleavage. After protection of thiols by S-sulfonation, this fragment was purified by gel permeation chromatography and reversed-phase high-performance liquid chromatography. The monomeric...

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PMID: 2153544
DOI: 10.1111/j.1432-1033.1990.tb15296.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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