Article
Molecular Diagnostics of Colorectal Cancer
1 May 2011
Abstract excerpt
CONTEXT: Of all gastrointestinal tract epithelial malignancies, molecular diagnostics has impacted colorectal cancer the most. Molecular testing can detect sporadic and inherited colorectal cancers that arise through the microsatellite instability pathway and can determine the efficacy of targeted drug therapy. OBJECTIVES: To review the microsatellite instability pathway of colorectal carcinoma carcinogenesis and...
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