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Article

Mechanism of inhibition of Bacillus anthracis spore outgrowth by the lantibiotic nisin.

ACS chemical biology - 15 Jul 2011

Gut Ian M, Blanke Steven R, van der Donk Wilfred A

Abstract excerpt

The lantibiotic nisin inhibits growth of vegetative Gram-positive bacteria by binding to lipid II, which disrupts cell wall biosynthesis and facilitates pore formation. Nisin also inhibits the outgrowth of bacterial spores, including spores of Bacillus anthracis, whose structural and biochemical properties are fundamentally different from those of vegetative bacteria. The molecular basis of nisin inhibition of...

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Identifiers

PMID: 21517116
DOI: 10.1021/cb1004178
PMCID: PMC3178273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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