Targeting extracellular pyrophosphates underpins the high selectivity of nisin

Abstract excerpt

The spread of infectious diseases and the increase in antibiotic resistance represent a life-threatening global development that calls for new approaches to control microorganisms. Of all potential targets, the essential and unique pathway of bacterial cell wall synthesis, targeted by the first known antibiotic penicillin, remains a perfect candidate for the development of new antibiotics. Here we show that the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacterial Genetics and Biotechnology
• Share to Bacteriophages and microbial interactions
• Share to Pneumonia and Respiratory Infections