Article
Evidence for the Effect of Vaccination on Host-Pathogen Interactions in a Murine Model of Pulmonary Tuberculosis by Mycobacterium tuberculosis.
Frontiers in immunology - 1 Jan 2020
Zatarain-Barrón Zyanya Lucia, Ramos-Espinosa Octavio, Marquina-Castillo Brenda, Barrios-Payán Jorge, Cornejo-Granados Fernanda, Maya-Lucas Otoniel, López-Leal Gamaliel, Molina-Romero Camilo, Anthony Richard M, Ochoa-Leyva Adrián, De La Rosa-Velázquez Inti Alberto, Rebollar-Vega Rosa Gloria, Warren Robin M, Mata-Espinosa Dulce Adriana, Hernández-Pando Rogelio, van Soolingen Dick
Abstract excerpt
The global control of Tuberculosis remains elusive, and Bacillus Calmette-Guérin (BCG) -the most widely used vaccine in history-has proven insufficient for reversing this epidemic. Several authors have suggested that the mass presence of vaccinated hosts might have affected the Mycobacterium tuberculosis (MTB) population structure, and this could in turn be reflected in a prevalence of strains with higher ability...
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