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Article

Association of CTLA4 gene polymorphisms with lymphatic filariasis in an East Malaysian population.

Human immunology - 1 Jul 2011

Idris Zulkarnain Md, Miswan Noorizan, Muhi Jamail, Mohd Tajul Ariffin Awang, Kun Jürgen F J, Noordin Rahmah

Abstract excerpt

Lymphatic filariasis (LF) is a parasitic disease caused by threadlike worms of the Brugia and Wuchereria species that live in the human lymphatic system. Regulatory T cells (Tregs) may play a key role in the pathogenesis of LF, and cytotoxic T-lymphocyte antigen-4 (CTLA4) expressed by Tregs is a potential candidate gene because it modulates T-cell activation. A case-control study was performed to establish a...

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Source

Identifiers

PMID: 21513760
DOI: 10.1016/j.humimm.2011.03.017

Genes

CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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