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Article

Single nucleotide polymorphisms in the angiogenic and lymphangiogenic pathways are associated with lymphedema caused by Wuchereria bancrofti.

Human genomics - 9 Nov 2017

Debrah Linda Batsa, Albers Anna, Debrah Alexander Yaw, Brockschmidt Felix F, Becker Tim, Herold Christine, Hofmann Andrea, Osei-Mensah Jubin, Mubarik Yusif, Fröhlich Holger, Hoerauf Achim, Pfarr Kenneth

Abstract excerpt

BACKGROUND: Lymphedema (LE) is a chronic clinical manifestation of filarial nematode infections characterized by lymphatic dysfunction and subsequent accumulation of protein-rich fluid in the interstitial space-lymphatic filariasis. A number of studies have identified single nucleotide polymorphisms (SNPs) associated with primary and secondary LE. To assess SNPs associated with LE caused by lymphatic filariasis,...

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Identifiers

PMID: 29122006
DOI: 10.1186/s40246-017-0121-7
PMCID: PMC5679374

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