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Article

FOXC2 and FLT4 Gene Variants in Lymphatic Filariasis.

Lymphatic research and biology - 1 Jun 2015

Sheik Yasmeen, Qureshi Sameera Fatima, Mohhammed Basheeruddin, Nallari Pratibha

Abstract excerpt

Lymphatic filariasis is the leading cause of secondary lymphedema wherein lymph transport is impaired due to lymphatic damage. FLT4 signaling and transcription factors such as FOXC2 play an important role in this type of lymphangiogenesis process induced by filarial parasites. The present study aims to assess the association of FLT4 and FOXC2 genes in lymphatic development/remodeling in lymphatic filariasis. A...

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Source

Identifiers

PMID: 26091406
DOI: 10.1089/lrb.2014.0025

Genes

FLT4
FOXC2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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