Article
Do the aryl hydrocarbon receptor interacting protein variants (Q228K and Q307R) play a role in patients with familial and sporadic hormone-secreting pituitary adenomas?
Genetic testing and molecular biomarkers - 1 Jul 2015
Yarman Sema, Ogret Yeliz Duvarci, Oguz Fatma Savran
Abstract excerpt
AIM: The aim of this study was to examine mutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene by sequence analysis of exons 1-6 using leukocyte genomic DNA obtained from a cohort of familial isolated pituitary adenoma (FIPA) and apparent sporadic functional pituitary adenoma Turkish patients. METHODS: Fourteen FIPA and 90 sporadic pituitary adenoma (somatotrophinoma, prolactinoma, and...
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