Variant within the promoter region of the CHRNA3 gene associated with FTN dependence is not related to self-reported willingness to quit smoking.

doi:10.1093/ntr/ntr084

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Article

Variant within the promoter region of the CHRNA3 gene associated with FTN dependence is not related to self-reported willingness to quit smoking.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 Sept 2011

Marques-Vidal Pedro, Kutalik Zoltán, Paccaud Fred, Bergmann Sven, Waeber Gérard, Vollenweider Peter, Cornuz Jacques

Abstract excerpt

INTRODUCTION: Common variation in the CHRNA5-CHRNA3-CHRNB4 gene region is robustly associated with smoking quantity. Conversely, the association between one of the most significant single nucleotide polymorphisms (SNPs; rs1051730 within the CHRNA3 gene) with perceived difficulty or willingness to quit smoking among current smokers is unknown. METHODS: Cross-sectional study including current smokers, 502 women,...

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Identifiers

PMID: 21511889
DOI: 10.1093/ntr/ntr084

Genes

CHRNA3
CHRNA5
CHRNB4

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Source receipt: pubmed, retrieved 7 Sept 2026.

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