A novel smoking cessation behavior based on quit attempts may identify new genes associated with long-term abstinence.

Abstract excerpt

BACKGROUND: Smoking cessation at any age has been shown to improve quality of life, decrease illness, and reduce mortality. About half of smokers attempt to quit each year, but only ∼ 7 % maintain long-term abstinence unaided. Few genetic factors have been consistently associated with smoking cessation, possibly due to poor phenotype definition. METHODS: We performed a genome-wide association study (GWAS) with an...

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