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Article

Single-nucleotide polymorphisms in genes related to the hypothalamic-pituitary-adrenal axis as risk factors for posttraumatic stress disorder.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Oct 2017

Carvalho Carolina M, Coimbra Bruno M, Ota Vanessa K, Mello Marcelo F, Belangero Sintia I

Abstract excerpt

Posttraumatic stress disorder (PTSD) is a common psychiatric disorder. The etiology of PTSD is multifactorial, depending on many environmental and genetic risk factors, and the exposure to life or physical integrity-threatening events. Several studies have shown significant correlations of many neurobiological findings with PTSD. Hypothalamic-pituitary-adrenal (HPA) axis dysfunction is strongly correlated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hypothalamo-Hypophyseal System

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Source

Identifiers

PMID: 28686326
DOI: 10.1002/ajmg.b.32564

Genes

CRHR1
CRHR2
FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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