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Article

B-cell receptors and heavy chain diseases: guilty by association?

Blood - 30 Jun 2011

Corcos Daniel, Osborn Michael J, Matheson Louise S

Abstract excerpt

Heavy chain diseases (HCDs) are B-cell proliferative disorders characterized by the production of monoclonal, incomplete, immunoglobulin (Ig) heavy chains (HCs) without associated light chains (LCs). These abnormal HCs are produced as a consequence of HC gene alterations in the neoplastic B cells. HC gene alterations will also impact on surface HC, which is part of the B-cell receptor (BCR), a crucial player in...

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Identifiers

PMID: 21508409
DOI: 10.1182/blood-2011-02-336164

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BCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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