Article
Nominal association between a polymorphism in DGKH and bipolar disorder detected in a meta-analysis of East Asian case-control samples.
Psychiatry and clinical neurosciences - 1 Apr 2011
Takata Atsushi, Kawasaki Hiroaki, Iwayama Yoshimi, Yamada Kazuo, Gotoh Leo, Mitsuyasu Hiroshi, Miura Tomofumi, Kato Tadafumi, Yoshikawa Takeo, Kanba Shigenobu
Abstract excerpt
AIM: Recent genome-wide association studies (GWAS) of bipolar disorder (BD) have detected new candidate genes, including DGKH, DFNB31 and SORCS2. However, the results of these GWAS were not necessarily consistent, indicating the importance of replication studies. In this study, we tested the genetic association of DGKH, DFNB31 and SORCS2 with BD. METHODS: We genotyped 18 single-nucleotide polymorphisms (SNP) in...
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