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Article

Combinatorial effect of maytansinol and radiation in Drosophila and human cancer cells.

Disease models & mechanisms - 1 Jul 2011

Edwards Anthony, Gladstone Mara, Yoon Petros, Raben David, Frederick Barbara, Su Tin Tin

Abstract excerpt

Combination therapy, in which two or more agents are applied, is more effective than single therapies for combating cancer. For this reason, combinations of chemotherapy with radiation are being explored in clinical trials, albeit with an empirical approach. We developed a screen to identify, from the onset, molecules that act in vivo in conjunction with radiation, using Drosophila as a model. Screens through two...

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Identifiers

PMID: 21504911
DOI: 10.1242/dmm.006486
PMCID: PMC3124055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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