Article
Association of toll-like receptor 9 gene polymorphism in Chinese patients with systemic lupus erythematosus in Taiwan.
Rheumatology international - 1 Jul 2012
Huang Chung-Ming, Huang Po-Hao, Chen Chi-Lan, Lin Ying-Ju, Tsai Chang-Hai, Huang Wen-Liang, Tsai Fuu-Jen
Abstract excerpt
The purpose of this study was to determine whether toll-like receptor 9 (TLR9) gene polymorphisms were markers of susceptibility to or severity of systemic lupus erythematosus (SLE) in Taiwanese patients. The study included 211 healthy individuals and 167 Chinese patients with SLE. Polymorphisms of TLR9 [rs2066807 and rs187084 (-1486 T/C)] were typed from genomic DNA. The genotypes, allelic frequencies, and...
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