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Article

Further clarification of the contribution of the ADH1C gene to vulnerability of alcoholism and selected liver diseases.

Human genetics - 1 Aug 2012

Li Dawei, Zhao Hongyu, Gelernter Joel

Abstract excerpt

The alcohol dehydrogenase 1C (ADH1C) subunit is an important member of the alcohol dehydrogenase family, a set of genes that plays a major role in the catabolism of ethanol. Numerous association studies have provided compelling evidence that ADH1C gene variation (formerly ADH3) is associated with altered genetic susceptibility to alcoholism and alcohol-related liver disease, cirrhosis, or pancreatitis. However,...

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Identifiers

PMID: 22476623
DOI: 10.1007/s00439-012-1163-5
PMCID: PMC3557796

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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