Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dopamine receptor D3 genetic polymorphism (rs6280TC) is associated with rates of cognitive impairment in methamphetamine-dependent men with HIV: preliminary findings.

Journal of neurovirology - 1 Jun 2011

Gupta Saurabh, Bousman Chad A, Chana Gursharan, Cherner Mariana, Heaton Robert K, Deutsch Reena, Ellis Ronald J, Grant Igor, Everall Ian P

Abstract excerpt

Macrophages are one of HIV-1's principal targets and chiefly responsible for translocating HIV into the central nervous system (CNS). Previous research suggested an increase in macrophages being infected by HIV in the presence of methamphetamine (METH) or increased extracellular dopamine (DA). Experimental studies indicate that this is mediated by DA receptors, including DA receptor D3 (DRD3), which is expressed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amphetamine-Related Disorders
Share to Cognition Disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dopamine

Share to HIV Infections

Share to Methamphetamine

Share to Neuropsychological Tests

Share to Receptors, Dopamine D3

Source

Open in PubMed Open full text

Identifiers

PMID: 21491142
DOI: 10.1007/s13365-011-0028-3
PMCID: PMC3151555

Genes

DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dopamine receptor D3 genetic polymorphism (rs6280TC) is associated with rates of cognitive impairment in methamphetamine-dependent men with HIV: preliminary findings.PMID 21491142Read ↗

DRD2 and DRD4 genes related to cognitive deficits in HIV-infected adults who abuse alcohol.Semantic proximity Read ↗

Functional polymorphisms in dopamine-related genes: Effect on neurocognitive functioning in HIV+ adultsSemantic proximity Read ↗

A genome-wide association study of methamphetamine use among people with HIV.Semantic proximity Read ↗

Role of APOC3 3238C/G polymorphism in HIV-associated neurocognitive disorder.Semantic proximity Read ↗

The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia.Semantic proximity Read ↗

HIV serostatus differs by catechol-O-methyltransferase Val158Met genotype.Semantic proximity Read ↗

Epigenetic Alterations in the Brain Associated with HIV-1 Infection and Methamphetamine DependenceSemantic proximity Read ↗

Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study.Semantic proximity Read ↗

Alcohol abuse and HIV infection: role of DRD2.Semantic proximity Read ↗

The role of host genetics in the susceptibility for HIV-associated neurocognitive disorders.Semantic proximity Read ↗

APOE epsilon4 and MBL-2 O/O genotypes are associated with neurocognitive impairment in HIV-infected plasma donors.Semantic proximity Read ↗

Polymorphisms in the Dopaminergic Receptor D3 Gene Correlate with Disease Progression Rate in Relapsing-Remitting Multiple Sclerosis Patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.