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Article

Functional polymorphisms in dopamine-related genes: Effect on neurocognitive functioning in HIV+ adults

14 Nov 2011

Abstract excerpt

UNLABELLED: Dopaminergic dysfunction is a putative mechanism underlying HIV-associated neurocognitive disorders. Dopamine transporter (DAT), brain-derived neurotrophic factor (BDNF), and catechol-O-methyltransferase (COMT) have been specifically implicated. We report analyses examining the main effects of functional polymorphisms within dopamine-modulating genes, as well as their interactive effects with disease...

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PMID: 22082040
DOI: 10.1080/13803395.2011.623118

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