Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chromatin organization in sperm may be the major functional consequence of base composition variation in the human genome.

PLoS genetics - 1 Apr 2011

Vavouri Tanya, Lehner Ben

Abstract excerpt

Chromatin in sperm is different from that in other cells, with most of the genome packaged by protamines not nucleosomes. Nucleosomes are, however, retained at some genomic sites, where they have the potential to transmit paternal epigenetic information. It is not understood how this retention is specified. Here we show that base composition is the major determinant of nucleosome retention in human sperm,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Composition
Share to Chromatin
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Human

Share to Models, Biological

Share to Nucleosomes

Share to Spermatozoa

Share to Transcription Initiation Site

Source

Open in PubMed Open full text

Identifiers

PMID: 21490963
DOI: 10.1371/journal.pgen.1002036
PMCID: PMC3072381

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chromatin organization in sperm may be the major functional consequence of base composition variation in the human genome.PMID 21490963Read ↗

Histone variants, nucleosome assembly and epigenetic inheritance.Semantic proximity Read ↗

Nucleosomes in mammalian sperm: conveying paternal epigenetic inheritance or subject to reprogramming between generations?Semantic proximity Read ↗

Widespread signatures of recent selection linked to nucleosome positioning in the human lineage.Semantic proximity Read ↗

Histone variants: essential actors in male genome programming.Semantic proximity Read ↗

Coupling between Sequence-Mediated Nucleosome Organization and Genome Evolution.Semantic proximity Read ↗

Histone variants--ancient wrap artists of the epigenome.Semantic proximity Read ↗

Contribution of the paternal histone epigenome to the preimplantation embryoSemantic proximity Read ↗

Nucleosome positioning stability is a significant modulator of germline mutation rate variation across the human genomeSemantic proximity Read ↗

Histone variants and epigenetic inheritance.Semantic proximity Read ↗

Histone variants and epigenetics.Semantic proximity Read ↗

DNA methylation in bull spermatozoa: evolutionary impacts, interindividual variability, and contribution to the embryoSemantic proximity Read ↗

Organization of chromosomes in spermatozoa: an additional layer of epigenetic information?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.