Article
Thrombomodulin phenotype of a distinct monocyte subtype is an independent prognostic marker for disseminated intravascular coagulation.
Critical care (London, England) - 1 Jan 2011
Hwang Sang Mee, Kim Ji-Eun, Han Kyou-Sup, Kim Hyun Kyung
Abstract excerpt
INTRODUCTION: Thrombomodulin, which is expressed solely on monocytes, along with tissue factor (TF), takes part in coagulation and inflammation. Circulating blood monocytes can be divided into 3 major subtypes on the basis of their receptor phenotype: classical (CD14brightCD16negative, CMs), inflammatory (CD14brightCD16positive; IMs), and dendritic cell-like (CD14dimCD16positive DMs). Monocyte subtype is strongly...
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