Article
A Pooled Sequencing Approach Identifies a Candidate Meiotic Driver in Drosophila.
Genetics - 1 May 2017
Wei Kevin H-C, Reddy Hemakumar M, Rathnam Chandramouli, Lee Jimin, Lin Deanna, Ji Shuqing, Mason James M, Clark Andrew G, Barbash Daniel A
Abstract excerpt
Meiotic drive occurs when a selfish element increases its transmission frequency above the Mendelian ratio by hijacking the asymmetric divisions of female meiosis. Meiotic drive causes genomic conflict and potentially has a major impact on genome evolution, but only a few drive loci of large effect have been described. New methods to reliably detect meiotic drive are therefore needed, particularly for discovering...
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