Recognition of yeast nucleic acids triggers a host‐protective type I interferon response

Abstract excerpt

Although type I interferons (IFN-α/β) have been traditionally associated with antiviral responses, their importance in host defense against bacterial pathogens is being increasingly appreciated. Little is known, however, about the occurrence and functional role of IFN-α/β production in response to pathogenic yeasts. Here, we found that conventional DCs, but not macrophages nor plasmacytoid DCs, mounted IFN-β...

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