Article
B Cell Recognition of Candida albicans Hyphae via TLR 2 Promotes IgG1 and IL-6 Secretion for TH17 Differentiation.
Frontiers in immunology - 1 Jan 2021
Ferreira-Gomes Marta, Wich Melissa, Böde Sally, Hube Bernhard, Jacobsen Ilse D, Jungnickel Berit
Abstract excerpt
Candida albicans is usually a benign member of the human gut microbiota, but can become pathogenic under certain circumstances, for example in an immunocompromised host. The innate immune system, in particular neutrophils and macrophages, constitutes a crucial first line of defense against fungal invasion, however adaptive immunity may provide long term protection and thus allow vaccination of at risk patients....
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