Article
Lack of association of polymorphic variants of genes encoding zinc transporters with the risk of orofacial cleft-affected pregnancies.
Folia histochemica et cytobiologica - 1 Dec 2010
Hozyasz Kamil K, Mostowska Adrianna, Lianeri Margarita, Offert Barbara, Jagodzinski Pawel P
Abstract excerpt
Maternal zinc deficiency seems to be a risk factor for orofacial clefts in offspring. This study was undertaken to investigate the involvement of polymorphic variants of genes for zinc transporters in the susceptibility of clefting. PCRRFLP analysis was used to analyze single nucleotide polymorphisms of SLC30A1 (rs7526700, rs2278651, rs611386), SLC30A4 (rs2453531, rs8029246), SLC30A5 (, ,...
