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Mitochondrial insertion-deletion polymorphism: role in disease pathology.

Genetic testing and molecular biomarkers - 1 May 2011

Komandur Sreelatha, Venkatasubramanian Sambasivan, Alluri Ravindra Varma, Rao Pragna, Rao Prabhakar, Hasan Qurratulain

Abstract excerpt

AIM: Mitochondrial DNA (mtDNA) sequence variations are associated with a number of human diseases. The 9-bp repeat sequence, CCCCCTCTA, in the intergenic region of MTCO2 and MTTK genes of the mtDNA has been extensively used in phylogenic studies. The sequence has been reported to be polymorphic in south-east Asians in isolated cases of mt diseases. This is the first systemic study identifying the role of...

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Share to Cardiomyopathy, Dilated
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutagenesis, Insertional

Share to Nervous System Diseases

Share to Repetitive Sequences, Nucleic Acid

Share to RNA, Transfer, Lys

Share to Sequence Deletion

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Source

Identifiers

PMID: 21476899
DOI: 10.1089/gtmb.2010.0205

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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