Article
Updating the East Asian mtDNA phylogeny: a prerequisite for the identification of pathogenic mutations.
Human molecular genetics - 1 Jul 2006
Kong Qing-Peng, Bandelt Hans-Jürgen, Sun Chang, Yao Yong-Gang, Salas Antonio, Achilli Alessandro, Wang Cheng-Ye, Zhong Li, Zhu Chun-Ling, Wu Shi-Fang, Torroni Antonio, Zhang Ya-Ping
Abstract excerpt
Knowledge about the world phylogeny of human mitochondrial DNA (mtDNA) is essential not only for evaluating the pathogenic role of specific mtDNA mutations but also for performing reliable association studies between mtDNA haplogroups and complex disorders. In the past few years, the main features of the East Asian portion of the mtDNA phylogeny have been determined on the basis of complete sequencing efforts,...
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