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[The effects of cytochrome P450 2C19 genetic polymorphism on clopidogrel resistance and recent prognosis of patients with acute coronary syndrome].

Zhonghua nei ke za zhi - 1 Nov 2013

Li Shao-nan, Liu Zhen, Luo Yi, Chen Ping-an, Lei Xiao-ming, Li Guang-lian

Abstract excerpt

OBJECTIVE: To investigate the relationship between cytochrome P450 (CYP) 2C19 genetic polymorphism and clopidogrel resistance(CR) in patients with acute coronary syndrome(ACS), and to assess the effects of genetic polymorphism at CYP2C19 (681G>A) on the prognosis of ACS patients. METHODS: A total of 462 patients with ACS were enrolled and received loading dose clopidogrel(600 mg). The blood samples of patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24439192

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