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Article

Relation of genetic polymorphisms in the cytochrome P450 gene with clopidogrel resistance after drug-eluting stent implantation in Koreans.

The American journal of cardiology - 1 Jul 2009

Lee Jung Myung, Park Sungha, Shin Dong-Jik, Choi Donghoon, Shim Chi Young, Ko Young-Guk, Kim Jung-Sun, Shin Eun-Soon, Chang Chong Won, Lee Jong-Eun, Jang Yangsoo

Abstract excerpt

Clopidogrel is a prodrug that has to be converted to an active metabolite by hepatic cytochrome P450 (CYP) isoenzymes to inhibit platelet aggregation. Individual variability of platelet inhibition by clopidogrel suggests a possibility for genetic factors having a significant influence on clopidogrel responsiveness. In this study, we sought to determine the relation of genetic polymorphisms of CYP genes to...

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Source

Identifiers

PMID: 19576320
DOI: 10.1016/j.amjcard.2009.02.045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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