Article
Both Th2 and Th17 responses are involved in the pathogenesis of Churg-Strauss syndrome.
Clinical and experimental rheumatology - 1 Jan 2000
Jakiela Bogdan, Sanak Marek, Szczeklik Wojciech, Sokolowska Barbara, Plutecka Hanna, Mastalerz Lucyna, Musial Jacek, Szczeklik Andrzej
Abstract excerpt
OBJECTIVES: Churg-Strauss syndrome (CSS) is a rare systemic vasculitis associated with eosinophilia and granuloma formation. The contribution of individual T-helper cell lineages in pathogenesis of CSS is unknown. We hypothesised that in CSS an imbalance of major effector T-cell subpopulations ta...
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