Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL-10 expression is regulated by HPV E2 protein in cervical cancer cells

25 Jan 2011

Abstract excerpt

It has been found that certain cytokines (IL-4, IL-10 and TGF-β1) are highly expressed locally in biopsies from patients with premalignant lesions and cervical cancer, and may induce a local immune-suppression state. In particular, IL-10 is highly expressed in tumor cells and its expression is directly proportional to the development of HPV-positive cervical cancer, suggesting an important role of HPV proteins in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cervical Cancer and HPV Research
Share to Immune Response and Inflammation
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21468579
DOI: 10.3892/mmr.2011.429

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL-10 expression is regulated by HPV E2 protein in cervical cancer cellsPMID 21468579Read ↗

IL-10 Promotes Tumor Aggressiveness via Upregulation of CIP2A Transcription in Lung AdenocarcinomaSemantic proximity Read ↗

IL-10 gene polymorphism c.-592C>A increases HPV infection susceptibility and influences IL-10 levels in HPV infected women.Semantic proximity Read ↗

E6 and E7 Oncoproteins from Human Papillomavirus Type 16 Induce Activation of Human Transforming Growth Factor <i>β</i> <sub>1</sub> Promoter throughout Sp1 Recognition SequenceSemantic proximity Read ↗

Interleukin-10 production by tumor infiltrating macrophages plays a role in Human Papillomavirus 16 tumor growth.Semantic proximity Read ↗

Effect of anti-inflammatory (IL-4, IL-10) cytokine genes in relation to risk of cervical carcinoma.Semantic proximity Read ↗

The relationship between cytokines and HPV-16, HPV-16 E6, E7, and high-risk HPV viral load in the uterine cervix.Semantic proximity Read ↗

Dose-dependent regulation of the early promoter of human papillomavirus type 18 by the viral E2 proteinSemantic proximity Read ↗

An interleukin-10 gene polymorphism associated with the development of cervical lesions in women infected with Human Papillomavirus and using oral contraceptives.Semantic proximity Read ↗

Human Cytomegalovirus interleukin-10 promotes proliferation and migration of MCF-7 breast cancer cellsSemantic proximity Read ↗

The IL-10 -1082G polymorphism is associated with clearance of HPV infection.Semantic proximity Read ↗

Different mechanisms contribute to the E2-mediated transcriptional repression of human papillomavirus type 18 viral oncogenesSemantic proximity Read ↗

Interleukin-10 Increases Th1 Cytokine Production and Cytotoxic Potential in Human Papillomavirus-Specific CD8+Cytotoxic T LymphocytesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.