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Human Cytomegalovirus interleukin-10 promotes proliferation and migration of MCF-7 breast cancer cells

18 Mar 2015

Abstract excerpt

family that is widespread in the general population and has been linked to several forms of cancer. While HCMV DNA has been found in some breast cancer tissue specimens, we wanted to investigate whether a secreted viral cytokine might have an effect on cancerous or even pre-cancerous cells. HCMV encodes an ortholog of the human cellular cytokine interleukin-10 (IL-10). The HCMV UL111A gene product is cmvIL-10,...

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PMID: 26023679
DOI: 10.14800/ccm.678

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