Article
p120-catenin isoform 3 regulates subcellular localization of Kaiso and promotes invasion in lung cancer cells via a phosphorylation-dependent mechanism.
International journal of oncology - 1 Jun 2011
Zhang Peng-Xin, Wang Yan, Liu Yang, Jiang Gui-Yang, Li Qing-Chang, Wang En-Hua
Abstract excerpt
p120-catenin regulates E-cadherin stability at the plasma membrane as well as Rho GTPase activity in the cytoplasm, and also interacts with the transcriptional repressor, Kaiso, in the nucleus. However, the role of different isoforms and the phosphorylated state of p120-catenin in the nucleus is poorly understood. In the present study, we show that p120-catenin isoform 3 interacts with Kaiso in lung cancer cells...
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