Article
Genome-wide association studies in pediatric endocrinology.
Hormone research in paediatrics - 1 Jan 2011
Dauber Andrew, Hirschhorn Joel N
Abstract excerpt
Genome-wide association (GWA) studies are a powerful tool for understanding the genetic underpinnings of human disease. In this article, we briefly review the role and findings of GWA studies in type 1 diabetes, stature, pubertal timing, obesity, and vitamin D deficiency. We then discuss the present and future implications of these findings with regards to disease prediction, uncovering basic biology, and the...
Topics
- Child
- Diabetes Mellitus, Type 1
- Endocrinology
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Obesity
- Pediatrics
- Puberty
- Vitamin D Deficiency