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Article

Liver intestine-cadherin (CDH17) haplotype is associated with increased risk of hepatocellular carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 2006

Wang Xiao Qi, Luk John M, Garcia-Barcelo Mercè, Miao Xiaoping, Leung Pauline P, Ho David W, Cheung Siu Tim, Lam Brian Y, Cheung Cindy K, Wong Ashley S, Lau Silvana S, So Man Ting, Yu Wan Ching, Cai Qi, Liu Karen S, Hui Chee Kin, Lau George K, Poon Ronnie T P, Wong John, Fan Sheung Tat

Abstract excerpt

PURPOSE: Hepatocellular carcinoma (HCC), the most common form of liver cancer, is a leading cause of cancer death worldwide. We previously showed that aberrant mRNA splicing of the liver intestine-cadherin gene CDH17 in liver tissues was triggered by the specific constellation of two CDH17 single nucleotide polymorphisms (651T and IVS6+35G). CDH17 aberrant splicing was highly associated with tumor dissemination...

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Identifiers

PMID: 16951245
DOI: 10.1158/1078-0432.CCR-06-0558

Genes

CDH17

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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