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Article

Importance of NOD2/CARD15 gene variants for susceptibility to and outcome of sepsis in Turkish children.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies - 1 Mar 2012

Tekin Deniz, Dalgic Nazan, Kayaalti Zeliha, Soylemezoglu Tulin, Diler Betul, Kutlubay Busra Isin

Abstract excerpt

OBJECTIVE: Severe sepsis remains a leading cause of morbidity and mortality in children. Given the link to pathogenesis, polymorphisms in genes involved in infection and inflammation may influence the outcomes in patients with sepsis and septic shock. The role of mutations within the innate immunity receptor NOD2/CARD15 has recently been demonstrated as a risk factor for bacteremia and mortality in adult patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21460759
DOI: 10.1097/PCC.0b013e3182191c2e

Genes

NOD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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