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Article

Association between dietary folate intake and clinical outcome in head and neck squamous cell carcinoma.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Jan 2012

Kawakita D, Matsuo K, Sato F, Oze I, Hosono S, Ito H, Watanabe M, Yatabe Y, Hanai N, Hasegawa Y, Tajima K, Murakami S, Tanaka H

Abstract excerpt

BACKGROUND: The association between dietary folate intake, two polymorphisms in methylenetetrahydrofolate reductase (MTHFR) and thymidylate synthase (TYMS), and survival in head and neck squamous cell carcinoma (HNSCC) patients is not clarified. PATIENTS AND METHODS: We conducted a retrospective cohort study of 437 HNSCC patients treated at Aichi Cancer Center. We evaluated the survival impact of pretreatment...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Dehydrogenase (NADP)

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Source

Identifiers

PMID: 21460376
DOI: 10.1093/annonc/mdr057

Genes

TYMS
MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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