Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A rare variant in the visfatin gene (NAMPT/PBEF1) is associated with protection from obesity.

Obesity (Silver Spring, Md.) - 1 Aug 2009

Blakemore Alexandra I F, Meyre David, Delplanque Jerome, Vatin Vincent, Lecoeur Cecile, Marre Michel, Tichet Jean, Balkau Beverley, Froguel Philippe, Walley Andrew J

Abstract excerpt

Visfatin was recently reported as a novel adipokine encoded by the NAMPT (PBEF1) gene. This study was aimed at investigation of the possibility that single-nucleotide polymorphisms (SNPs) in the visfatin gene are associated with either obesity or type 2 diabetes (T2D). A set of eight "tag-SNPs" were selected and ABI SNPlex assays designed for genotyping purposes. A total of 1,709 severely obese subjects were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Mass Index
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Introns

Share to Linkage Disequilibrium

Share to Nicotinamide Phosphoribosyltransferase

Share to Obesity

Share to Odds Ratio

Source

Identifiers

PMID: 19300429
DOI: 10.1038/oby.2009.75

Genes

NAMPT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A rare variant in the visfatin gene (NAMPT/PBEF1) is associated with protection from obesity.PMID 19300429Read ↗

Genetic variation in the visfatin (PBEF1/NAMPT) gene and type 2 diabetes in the Greek population.Semantic proximity Read ↗

Association of genetic variability in selected regions in visfatin (NAMPT) gene with anthropometric parameters and dietary composition in obese and non-obese Central-European population.Semantic proximity Read ↗

A visfatin promoter polymorphism is associated with low-grade inflammation and type 2 diabetes.Semantic proximity Read ↗

Association of Visfatin gene polymorphism with obesity related metabolic disorders among Pakistani population: a case control study.Semantic proximity Read ↗

Genetic variation in the visfatin gene (PBEF1) and its relation to glucose metabolism and fat-depot-specific messenger ribonucleic acid expression in humans.Semantic proximity Read ↗

The effects of NAMPT haplotypes and metabolic risk factors on circulating visfatin/NAMPT levels in childhood obesity.Semantic proximity Read ↗

Visfatin and its genetic variants are associated with obesity-related morbidities and cardiometabolic risk in severely obese children.Semantic proximity Read ↗

The visfatin (PBEF1) G-948T gene polymorphism is associated with increased high-density lipoprotein cholesterol in obese subjects.Semantic proximity Read ↗

Effects of genetic variation in the visfatin gene (PBEF1) on obesity, glucose metabolism, and blood pressure in children.Semantic proximity Read ↗

Association between polymorphisms of the Nesfatin gene, NUCB2, and obesity in men.Semantic proximity Read ↗

The visfatin gene is associated with glucose and lipid metabolism in a Chinese population.Semantic proximity Read ↗

NAMPT gene rs2058539 variant is a risk factor for nonalcoholic fatty liver disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.