Potential impact of NUCB2 genetic variants with the clinicopathological characteristics of prostate cancer.

doi:10.7150/ijms.135299

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Article

Potential impact of NUCB2 genetic variants with the clinicopathological characteristics of prostate cancer.

International journal of medical sciences - 1 Jan 2026

Lee Yung-Shu, Lin Tien-Huang, Lin Chia-Yen, Yang Shun-Fa, Lin Chiao-Wen, Tang Chih-Hsin

Abstract excerpt

The most prevalent illness in men is prostate cancer, which risk increases with age and obesity. The precursor NUCB2 gene produces the adipokine nesfatin-1, which was first found in hypothalamic neurons. It is currently unclear how NUCB2 polymorphisms, cancer-promoting lifestyle factors, and prostate cancer are related. We investigated the relationship between clinicopathological features and 4 NUCB2 gene...

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Topics

Humans
Male
Nucleobindins
Prostatic Neoplasms
Polymorphism, Single Nucleotide
Genetic Predisposition to Disease
Aged
Middle Aged
Neoplasm Staging

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genotype

DNA-Binding Proteins

Prostate

Alleles

Source

Open in PubMed Open full text

Identifiers

PMID: 42694552
DOI: 10.7150/ijms.135299
PMCID: PMC13539920

Genes

NUCB2
TG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.