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Article

Molecular subclassification of diffuse gliomas: Seeing order in the chaos

28 Mar 2011

Abstract excerpt

Diffuse gliomas such as astrocytomas and oligodendrogliomas are the most common form of intrinsic brain tumor in adults. Even within a single pathologic class, these tumors are both histologically and molecularly diverse, although not randomly so. Recent large-scale genomic analyses have revealed patterns of molecular changes within tumor subclasses that harbor distinct underlying biology, clinical prognosis, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21446051
DOI: 10.1002/glia.21165

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