Article
An essential signaling role for the m3G cap in the transport of U1 snRNP to the nucleus.
Science (New York, N.Y.) - 17 Aug 1990
Fischer U, Lührmann R
Abstract excerpt
The major small nuclear ribonucleoprotein particles (snRNPs) U1, U2, U4 + U6, and U5 have to be transported from the cytoplasm, where they are synthesized, to the nucleus, where they splice pre-messenger RNAs. Since the free core snRNP proteins in the cytoplasm do not enter the nucleus on their o...
Topics
- Animals
- Biological Transport
- Cell Nucleus
- Cytoplasm
- Female
- Guanosine
- Kinetics
- Mutation
- Oocytes
- RNA Caps
- Ribonucleoproteins
- Ribonucleoproteins, Small Nuclear
- Signal Transduction
- Xenopus laevis