Article
Nucleolar localization elements in U8 snoRNA differ from sequences required for rRNA processing.
RNA (New York, N.Y.) - 1 Jul 1998
Lange T S, Borovjagin A V, Gerbi S A
Abstract excerpt
U8 small nucleolar RNA (snoRNA) is essential for metazoan ribosomal RNA (rRNA) processing in nucleoli. The sequences and structural features in Xenopus U8 snoRNA that are required for its nucleolar localization were analyzed. Fluorescein-labeled U8 snoRNA was injected into Xenopus oocyte nuclei, and fluorescence microscopy of nucleolar preparations revealed that wild-type Xenopus U8 snoRNA localized to nucleoli,...
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