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Article

Estrogen receptor α single nucleotide polymorphism modifies the risk of azoospermia in childhood cancer survivors.

Pharmacogenetics and genomics - 1 May 2011

Romerius Patrik, Giwercman Aleksander, Moëll Christian, Relander Thomas, Cavallin-Ståhl Eva, Wiebe Thomas, Halldén Christer, Giwercman Yvonne Lundberg

Abstract excerpt

OBJECTIVE: Cancer treatment in childhood leads to permanent azoospermia in a significant number of boys and those who are diagnosed with cancer before puberty do not have the option of pretreatment cryopreservation of spermatozoa. However, there is an interindividual variation in the sensitivity to gonadotoxic effects of cancer therapy, which probably is due to genetic factors. Identification of genetic markers...

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Identifiers

PMID: 21430602
DOI: 10.1097/FPC.0b013e328343a132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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