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Article

[Gene polymorphisms of estrogen receptor α correlated with hypospadias in children].

Zhonghua nan ke xue = National journal of andrology - 1 Jan 2017

Zhang Zhi-Hui, Wang Shu-Hui, Bai Ji-Xiang

Abstract excerpt

OBJECTIVE: To investigate the association of the polymorphisms of the gene of estrogen receptor α 1 (ESR1) with the risk of hypospadias in children of Northeast China. METHODS: This study included 95 hypospadias patients aged 3.2±0.6 years and 105 children aged 3.1±0.7 years as normal controls. Using PCR and gene sequencing, we determined the genotypes of the polymorphisms of ESR1 rs2077647 and rs6932902 in the...

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PMID: 29658239

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ESR1

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