Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of HER2 amplification in circulating free DNA in patients with breast cancer.

British journal of cancer - 12 Apr 2011

Page K, Hava N, Ward B, Brown J, Guttery D S, Ruangpratheep C, Blighe K, Sharma A, Walker R A, Coombes R C, Shaw J A

Abstract excerpt

BACKGROUND: Human epidermal growth factor receptor 2 (HER2) is amplified and overexpressed in 20-25% of breast cancers. This study investigated circulating free DNA (cfDNA) for detection of HER2 gene amplification in patients with breast cancer. METHODS: Circulating free DNA was extracted from plasma of unselected patients with primary breast cancer (22 before surgery and 68 following treatment), 30 metastatic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Carcinoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to Follow-Up Studies

Share to Gene Amplification

Share to Neoplasm Metastasis

Share to Receptor, ErbB-2

Source

Open in PubMed Open full text

Identifiers

PMID: 21427727
DOI: 10.1038/bjc.2011.89
PMCID: PMC3078598

Genes

CNTNAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Detection of HER2 amplification in circulating free DNA in patients with breast cancer.PMID 21427727Read ↗

Next Generation Sequencing of Circulating Cell-Free DNA for Evaluating Mutations and Gene Amplification in Metastatic Breast Cancer.Semantic proximity Read ↗

Detection of genomic alterations in breast cancer with circulating tumour DNA sequencing.Semantic proximity Read ↗

Longitudinal HER2 amplification tracked in circulating tumor DNA for therapeutic effect monitoring and prognostic evaluation in patients with breast cancerSemantic proximity Read ↗

Circulating-free DNA Mutation Associated with Response of Targeted Therapy in Human Epidermal Growth Factor Receptor 2-positive Metastatic Breast Cancer.Semantic proximity Read ↗

Circulating Tumor DNA in HER2-Amplified Breast Cancer: A Translational Research Substudy of the NeoALTTO Phase III TrialSemantic proximity Read ↗

Quantification of Free Circulating Tumor DNA as a Diagnostic Marker for Breast CancerSemantic proximity Read ↗

Cell-free DNA Concentration as a Biomarker of Response and Recurrence in HER2-Negative Breast Cancer Receiving Neoadjuvant ChemotherapySemantic proximity Read ↗

Plasma HER2 ( ERBB2 ) Copy Number Predicts Response to HER2-targeted Therapy in Metastatic Colorectal CancerSemantic proximity Read ↗

Identification of Somatic Mutations in Thirty-year-old Serum Cell-free DNA From Patients With Breast Cancer: A Feasibility Study.Semantic proximity Read ↗

<i>HER-2</i> gene amplification can be acquired as breast cancer progressesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.