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Brachyury-targeted immunotherapy combined with gemcitabine against head and neck cancer

2023-02-08

Abstract excerpt

Brachyury is a transcription factor belonging to the T-box gene family and is involved in the posterior formation of the mesoderm and differentiation of chordates. As the overexpression of Brachyury is a poor prognostic factor in a variety of cancers, the establishment of Brachyury-targeted therapy would be beneficial for the treatment of aggressive tumors. Because transcription factors are difficult to treat with...

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Literature Corpus work
1be98980-13e4-5049-8c12-8efc6c4bddf3
DOI
10.21203/rs.3.rs-2553923/v1
Open publication

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