Article
The T-box transcription factor Brachyury regulates epithelial-mesenchymal transition in association with cancer stem-like cells in adenoid cystic carcinoma cells.
BMC cancer - 29 Aug 2012
Shimoda Miyuki, Sugiura Tsuyoshi, Imajyo Ikumi, Ishii Kotaro, Chigita Satomi, Seki Katsuhiro, Kobayashi Yousuke, Shirasuna Kanemitsu
Abstract excerpt
BACKGROUND: The high frequencies of recurrence and distant metastasis of adenoid cystic carcinoma (AdCC) emphasize the need to better understand the biological factors associated with these outcomes. To analyze the mechanisms of AdCC metastasis, we established the green fluorescence protein (GFP)-transfected subline ACCS-GFP from the AdCC parental cell line and the metastatic ACCS-M GFP line from an in vivo...
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