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Article

Side population is not necessary or sufficient for a cancer stem cell phenotype in glioblastoma multiforme.

Stem cells (Dayton, Ohio) - 1 Mar 2011

Broadley Kate W R, Hunn Martin K, Farrand Kathryn J, Price Kylie M, Grasso Carole, Miller Rose J, Hermans Ian F, McConnell Melanie J

Abstract excerpt

There is strong evidence for the existence of cancer stem cells (CSCs) in the aggressive brain tumor glioblastoma multiforme (GBM). These cells have stem-like self-renewal activity and increased tumor initiation capacity and are believed to be responsible for recurrence due to their resistance to therapy. Several techniques have been used to enrich for CSC, including growth in serum-free defined media to induce...

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Identifiers

PMID: 21425408
DOI: 10.1002/stem.582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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