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Association of IL-6 Gene (-174 and -572 G/C) Polymorphisms with Proliferative Diabetic Retinopathy of Type 2 Diabetes in a Chinese Population.

Ophthalmic research - 1 Jan 2017

Lu Qin-Kang, Zhang Jun-Tao, Zhao Na, Wang Hui-Yun, Tong Qi-Hu, Wang Shou-Li

Abstract excerpt

PURPOSE: To investigate the association of interleukin (IL)-6 with proliferative diabetic retinopathy (PDR) of type 2 diabetes (T2D) in a Chinese population. METHODS: Two subtypes of the IL-6 promoter (-174 and -572 G/C) were genotyped in 215 T2D patients with PDR and 207 T2D patients with a normal retinal function (controls) using the PCR-RFLP method. The mRNA and protein expression of IL-6 was examined by...

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PMID: 28651253
DOI: 10.1159/000475670

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