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Article

Hsa-miR-34b is a plasma-stable microRNA that is elevated in pre-manifest Huntington's disease.

Human molecular genetics - 1 Jun 2011

Gaughwin Philip Michael, Ciesla Maciej, Lahiri Nayana, Tabrizi Sarah J, Brundin Patrik, Björkqvist Maria

Abstract excerpt

Huntington's disease (HD) is a devastating, neurodegenerative condition, which lacks effective treatment. Normal Huntingtin (HTT) and mutant Huntingtin (mHTT) are expressed in multiple tissues and can alter transcription of microRNAs (miRs). Importantly, miRs are present in a bio-stable form in human peripheral blood plasma and have recently been shown to be useful biomarkers in other diseases. We therefore...

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Source

Identifiers

PMID: 21421997
DOI: 10.1093/hmg/ddr111

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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